Campus Box 3290 Chapel Hill, NC 27599-3290, USA

Research Analytical

Analytical Research

Consistently ranked as one of the top analytical programs in the United States over the past four decades, the analytical division is recognized as a world leader in this scientific area.

Following the tradition set by the late Professor Charles N. Reilley, the division extends the frontier of measurement science through a focus on fundamental studies related to chemical analysis and the development of innovative instrumentation. All traditional areas of research are represented, including electrochemistry, mass spectrometry, microscopy, sensors, separations, single cell assays, micro- and nanoscale chemical measurement devices, and spectroscopy.

Research projects span a wide range of chemical analysis science, including microvolume separations and analysis, nanomaterials, proteomics, sensors, single cell/molecule analysis, and surface analysis; for examples of active research projects please see the list below.

The division has a strong alumni base with students working across academia, industry, and national labs enabling exciting career opportunities and networking for our graduate students.

Recent Research Results

Catalytic Nanomaterials

Creative approaches to the design of catalytic nanomaterials are necessary in achieving environmentally sustainable energy sources...

Goldwater Scholarship

Andrew Pendergast, a third-year undergraduate student, majoring in Chemistry, has been selected for the prestigious Goldwater Scholarship. Pendergast hopes to...

Hicks Earns Award

Iota Sigma PI, the National Honorary Society for Women in Chemistry, has selected Professor Leslie Hicks to receive the 2019 Agnes Fay...

Representative Publications

Electrosynthesis of High-Entropy Metallic Glass Nanoparticles for Designer, Multi-Functional Electrocatalysis.
Matthew W. Glasscott, Andrew D. Pendergast, Sondrica Goines, Anthony R. Bishop, Andy T. Hoang, Christophe Renault & Jeffrey E. Dick.
Nature Communications 10, Article number: 2650, 2019

Azide‑Alkyne Click Reactions to Prepare Chemically Modified Amorphous Carbon Electrodes.
Julia M. Fehr, Catherine G. McKenas, Benedict Liu, Matthew R.Lockett.
Applied Surface Science, Volume 480, 30 June 2019, Pages 1109-1115

Extended Nitric Oxide-Releasing Polyurethanes via S-Nitrosothiol-Modified Mesoporous Silica Nanoparticles.
Extended Nitric Oxide-Releasing Polyurethanes via S-Nitrosothiol-Modified Mesoporous Silica Nanoparticles.
ACS Appl. Mater. Interfaces, 2019, 11 (13), pp 12216–12223

Molecular Transport through Primary Human Small Intestinal Monolayers by Culture on a Collagen Scaffold with a Gradient of Chemical Cross-Linking.
Jennifer E. Speer, Dulan B. Gunasekara, Yuli Wang, John K. Fallon, Peter J. Attayek, Philip C. Smith, Christopher E. Sims and Nancy L. Allbritton.
Journal of Biological Engineering, 2019, 13:36

Fine-Tuning Porosity and Time-Resolved Observation of the Nucleation and Growth of Single Platinum Nanoparticles.
Matthew W. Glasscott and Jeffrey E. Dick.
ACS Nano, Article ASAP, Web 10.1021/acsnano.9b00546

“Fix and Assay”: Separating In-Cellulo Sphingolipid Reactions from Analytical Assay in Time and Space Using an Aldehyde-Based Fixative.
Angela Proctor and Nancy L. Allbritton.
Analyst, Volume: 144, Issue: 3, Pages: 961-971, FEB 7, 2019

Paper-Based Transwell Assays: An Inexpensive Alternative to Study Cellular Invasion.
Rachael M. Kenney, Adam Loeser, Nathan A. Whitman, and Matthew R. Lockett.
Analyst, 2019,144, 206-211

Advanced Characterization Techniques for Evaluating Porosity, Nanopore Tortuosity, and Electrical Connectivity at the Single Nanoparticle Level.
Matthew William Glasscott, Andrew David Pendergast, Moinul Choudhury, and Jeffrey E. Dick.
ACS Appl. Nano Mater., Just Accepted Manuscript, DOI: 10.1021/acsanm.8b02051