Mark Schoenfisch

Mark Schoenfisch

Peter A. Ornstein Distinguished Professor, Jointly appointed with the School of Medicine & School of Pharmacy

   Caudill Laboratories 336
   919-843-8714
   schoenfisch@unc.edu
  Group Website
    Curriculum Vitae


Research Interests

Analytical Sensors, Biomaterials & Nanoparticle Therapeutics


Professional Background

University of Kansas, B.A., 1992; University of Arizona, Ph.D., 1997; University of Michigan, National Institutes of Health Postdoctoral Fellow, 1998-1999; Society for Analytical Chemists of Pittsburgh Young Investigator Award, 2001; Eli Lilly and Company Young Investigator Award, 2002-2004; National Science Foundation CAREER Award, 2004-2009; International Union of Pure and Applied Chemistry Young Observer Award , 2005; John L. Sanders Award for Excellence in Undergraduate Teaching and Service, 2007; Chapman Family Teaching Award for Distinguished Teaching of Undergraduate Students, 2015


Research Synopsis

Our research is focused on four main areas: 1) designing macromolecular nitric oxide release vehicles as novel therapeutics; 2) improving the analytical performance of implantable continuous glucose monitoring devices for diabetes management; 3) designing microfluidic nitric oxide, NO, sensors for real-time detection of NO in biological media; and, 4) developing superhydrophobic interfaces for mold prevention and remediation. In the Schoenfisch Lab, we work at the interface of analytical chemistry, materials science, biomedical engineering, and biology. The types of multi-disciplinary research opportunities that are available include studies of therapeutics to treat various diseases; sensors that function reliably and continuously, real time, to facilitate disease management; microelectrode and microfluidic sensor design and fabrication for clinical, point-of-care, and diagnostic/prognostic applications; and, new macromolecular scaffolds that manipulate biology and physiology.

News & Publications

Cystic Fibrosis Therapeutic

Colonization of the lungs by biofilm-forming pathogens is a major cause of mortality in cystic fibrosis, CF. In CF patients, these pathogens are difficult...

 

Measuring Nitric Oxide

Nitric oxide, NO, is a molecule of vast physiological significance, but much remains unknown about the in vivo concentration dependence of its activity...