Research Archive

Mixed Tin-Titanium Oxides by Atomic Layer Deposition on Planar Substrates: Physical and Electronic Structure

Here we describe a workflow in which cell viability, drug penetration, and drug metabolism are quantified in a spatially resolved manner.

Modeling the Size Distribution and Chemical Composition of Secondary Organic Aerosols during the Reactive Uptake of Isoprene-Derived Epoxydiols under Low-Humidity Condition

Here, we implement our latest understanding of IEPOX-SOA formation within a box model to simulate the measured reactive uptake of IEPOX on polydisperse ammonium bisulfate seed aerosols within an environmental Teflon chamber.

Buffers, Especially the Good Kind

Here, I discuss some of the background regarding the genesis of “Good’s buffers”, make a few (disparaging) observations about the non-Good’s buffer, Tris, and suggest that we synthesize new buffers by combining the ideas of Good et al. with results from the past 60 years of protein chemistry.

Tunable Anion Exchange Membrane Conductivity and Permselectivity via Non-Covalent, Hydrogen Bond Cross-Linking

In an attempt to overcome this limitation, in this work we synthesized a series of anion exchange membranes containing non-covalent cross-links formed by a hydrogen bond donor (methacrylic acid) and a hydrogen bond acceptor (dimethylacrylamide).

Mechanistic investigation of a visible light mediated dehalogenation/cyclisation reaction using iron(iii), iridium(iii) and ruthenium(ii) photosensitizers

The mechanism of a visible light-driven dehalogenation/cyclization reaction was investigated using ruthenium(II), iridium(III) and iron(III) photosensitizers by means of steady-state photoluminescence, time-resolved infrared spectroscopy, and nanosecond/femtosecond transient absorption spectroscopy.

On the Determination of Halogen Atom Reduction Potentials with Photoredox Catalysts

Here, we report the use of two Ir(III) photoredox catalysts to initiate chloride, bromide, and iodide oxidation in organic solvents.

IreK-Mediated, Cell Wall-Protective Phosphorylation in Enterococcus faecalis

To better understand stress-modulated phosphorylation events contributing to antimicrobial resistance, wild type E. faecalis cells treated with cell wall-active antimicrobials, chlorhexidine or ceftriaxone, were examined via phosphoproteomics.

Alkyl–Aryl Cation Mixing in Chiral 2D Perovskites

We report 2D hybrid perovskites comprising a blend of chiral arylammonium and achiral alkylammonium spacer cations (1:1 mole ratio).

Machine-Learning-Guided Discovery of 19F MRI Agents Enabled by Automated Copolymer Synthesis

To tackle this challenge in the context of 19F magnetic resonance imaging (MRI) agents, we pursued a computer-guided materials discovery approach that combines synergistic innovations in automated flow synthesis and machine learning (ML) method development.

Quantifying the Effect of Multivalent Ions in Polyelectrolyte Solutions

This analysis shows that (i) there is only a small fraction of free counterions, f* < 12%; (ii) divalent ions have a strong effect on the renormalization of the excluded volume, reducing it by a factor of 2; and (iii) the effect of divalent counterions is much weaker on the renormalization of the Kuhn length, accounting for an increase of up to 10%.

Simultaneous fMRI and fast-scan cyclic voltammetry bridges evoked oxygen and neurotransmitter dynamics across spatiotemporal scales

Here, we propose an experimental setting enabling simultaneous fast-scan cyclic voltammetry (FSCV) and blood oxygenation level-dependent functional magnetic imaging (BOLD fMRI) to measure both local tissue oxygen and dopamine responses, and global BOLD changes, respectively.

Brønsted Acid Catalyzed Stereoselective Polymerization of Vinyl Ethers

Here, we demonstrate the first Brønsted acid catalyzed stereoselective polymerization of vinyl ethers.