Research Archive

To better understand stress-modulated phosphorylation events contributing to antimicrobial resistance, wild type E. faecalis cells treated with cell wall-active antimicrobials, chlorhexidine or ceftriaxone, were examined via phosphoproteomics.

We report 2D hybrid perovskites comprising a blend of chiral arylammonium and achiral alkylammonium spacer cations (1:1 mole ratio).

To tackle this challenge in the context of 19F magnetic resonance imaging (MRI) agents, we pursued a computer-guided materials discovery approach that combines synergistic innovations in automated flow synthesis and machine learning (ML) method development.

This analysis shows that (i) there is only a small fraction of free counterions, f* < 12%; (ii) divalent ions have a strong effect on the renormalization of the excluded volume, reducing it by a factor of 2; and (iii) the effect of divalent counterions is much weaker on the renormalization of the Kuhn length, accounting for an increase of up to 10%.

Here, we propose an experimental setting enabling simultaneous fast-scan cyclic voltammetry (FSCV) and blood oxygenation level-dependent functional magnetic imaging (BOLD fMRI) to measure both local tissue oxygen and dopamine responses, and global BOLD changes, respectively.

Here, we demonstrate the first Brønsted acid catalyzed stereoselective polymerization of vinyl ethers.

Here, we apply LOVE NMR, Fourier transform infrared spectroscopy, and solution hydrogen–deuterium exchange to globular proteins GB1, CI2, and two variants thereof to link mutation-induced changes in the dehydrated protein structure to changes in solution structure and stability.

Presented here are high-precision all-electron RT-TDDFT and it-TDDFT implementations within a numerical atom-centered orbital (NAO) basis function framework in the FHI-aims code.

Here, we discuss this recent work and the emerging picture of protein surfaces as not just hydrophilic coats interfacing the solvent to the protein's core and functional regions, but as critical components in cells controlling protein mobility, function and communication with post-translational modifications.

This work demonstrates that poly(silyl ether)s can be derived from poly(acyl silane)s through Brook rearrangements and Brook/benzoin sequences. Such skeletal editing is a powerful strategy to install functionality and modify properties of polymeric materials.

This work demonstrates that industrially-relevant vinyl polymers can be derived from polyesters through a sigmatropic rearrangement. Such editing of the polymer skeleton leads to dramatic changes in the thermal properties of the materials, and provides access to novel polymer compositions and structural precision.

In this work, we compare the optoelectronic properties and photoelectrochemical performance of two D–A–D structural isomers with thiophene-X-carboxylic acid (X denotes 3 and 2 positions) derivatives and 2,1,3-benzothiadiazole as the D and A moieties, respectively.