Research Archive

Observationally Constrained Modeling of the Reactive Uptake of Isoprene-Derived Epoxydiols under Elevated Relative Humidity and Varying Acidity of Seed Aerosol Conditions

Here, we use simultaneous environmental chamber measurements of multiple parameters governing IEPOX-SOA formation at timescales of ∼hours: particle size distribution, composition, and volatility of IEPOX-SOA to constrain the key parameters governing IEPOX-SOA formation under humid (i.e., 50% relative humidity, RH) and varying seed aerosol acidity conditions.

Sticky Architecture: Encoding Pressure Sensitive Adhesion in Polymer Networks

Herein, we develop a precise additive-free PSA design platform that predictably leverages polymer network architecture to empower comprehensive control over adhesive performance.

Water splitting with silicon p-i-n superlattices suspended in solution

Here we report Si-based PSRs by synthesizing high-photovoltage multijunction Si nanowires (SiNWs) that are co-functionalized to catalytically split water.

Electroabsorption as a Probe of Electrons Injected into Nanocrystalline SnO2/TiO2 Core/Shell Thin Films

Here we report electroabsorption studies designed to quantify the surface electric field and the ability of the shell to screen an electric field from a surface anchored dye.

Theoretical upper bound of multiplexing in biological sensory receptors

Through a Langevin dynamics simulation of a ligand-receptor sensor in a bath of ligands, we demonstrate that a binary-state receptor can simultaneously encode multiple independent environmental variables, such as ligand concentration and the speed of media flow.

Versatile Triphenylphosphine-Containing Polymeric Catalysts and Elucidation of Structure–Function Relationships

We synthesized a panel of polymeric catalysts containing a novel triphenylphosphine acrylamide monomer and investigated how their properties impact the rate of a model Suzuki–Miyaura cross-coupling reaction.

Investigating Fundamental Principles of Nonequilibrium Assembly Using Temperature-Sensitive Copolymers

Using a model system of poly(ethylene glycol) methacrylate-based thermoresponsive lower critical solution temperature (LCST) copolymers, we explored the impact of composition and stimulus path on nonequilibrium thermal hysteretic behavior.

Single-Molecule Correlated Chemical Probing: A Revolution in RNA Structure Analysis

Enabled by a specialized reverse transcription strategy called mutational profiling (MaP), multiple chemical modification events can be measured within individual RNA molecules.

In Situ Attenuated Total Reflectance Infrared Spectroelectrochemistry (ATR-IR-SEC) for the Characterization of Molecular Redox Processes on Surface-Proximal Doped Silicon ATR Crystal Working Electrodes

Here, we have developed a new strategy to use multiple-reflection attenuated total reflectance IR spectroscopy (ATR-IR) coupled with electrochemistry to characterize catalysts directly integrated with a semiconductor surface under applied potential.

Innovations in targeting RNA by fragment-based ligand discovery

Here we share an integrated analysis of recent innovations in FBLD, emphasizing opportunities resulting from fragment elaboration via both linking and growing.

Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut

Here we survey the diversity of BSHs in the gut commensals Lactobacillaceae, which are commonly used as probiotics, and other members of the human gut microbiome.

Macromolecular Crowding by Polyethylene Glycol Reduces Protein Breathing

We used NMR to assess the effects of ethylene glycol (EG) and polyethylene glycols (PEGs) on the structure and stability of the B1 domain of protein G (GB1).