Simon Meek

Simon Meek

Associate Professor

   Venable Hall 1307
  Group Website
  Curriculum Vitae

Research Interests

Organic Synthesis, Organometallic Chemistry, Catalysis

Research Synopsis

Research in my group is involved with the discovery, design, and development of new chiral catalysts and catalytic methods for chemical synthesis. We focus on developing practical and effective catalysts that enable the use of simple and abundant starting materials for useful carbon-carbon and carbon- heteroatom bond forming reactions.

We are interested in understanding reaction mechanisms, efficiency and selectivity, as well as demonstrating and challenging our catalytic transformations, reliablility, in efficient enantioselective total synthesis of complex biologically important molecules. Areas of interest in my research program include catalysis, stereoselective organic synthesis, and organometallic chemistry.

Professional Background

M.Chem., University of Sheffield, 2003; Ph.D., University of Sheffield, 2006; Postdoctoral Fellow, Boston College, 2006-2011

News & Publications

We have developed an efficient site- and stereoselective dicarbofunctionalization fragment coupling between aldehydes, dienes, and arylboronic acids for the synthesis of enantioenriched bis-homoallylic alcohols.


A general method for the synthesis of secondary homoallylic alcohols containing α-quaternary carbon stereogenic centers in high diastereo- and enantioselectivity (up to >20:1 dr and >99:1 er) is disclosed.