Gary Pielak

Gary Pielak

Kenan Distinguished Professor of Chemistry, Biochemistry and Biophysics; Vice Chair of Facilities; Jointly appointed with the School of Medicine

   Genome Sciences Building 3250
  Group Website
  Curriculum Vitae

Research Interests

Protein Biophysics Emphasizing Studies in Living Cells

Research Synopsis

My graduate students and I work in three areas:
High-resolution protein NMR studies in living cells.
Oxidative damage to α-synuclein, a key protein in Parkinson's disease.
Pressure perturbation calorimetry of peptides and proteins.

Professional Background

BS Chem., Bradley U, 1977; PhD Biochemistry, with J. Ivan Legg, Washington State U, 1983; Postdoc with Michael Smith, U British Columbia, 1983-1986; Postdoc with Robert JP Williams, Oxford. 1986-1988; DuPont Young Faculty Award; Morrow Young Faculty Award; NIH Pioneer Award, 2006; National Science Foundation Program Director 2013-2014

Research Group

News & Publications

Cells survive fluctuations in osmolality by accumulating and depleting highly soluble, usually neutral, small organic...


The tradition of "Aloha Friday" in the department of chemistry was revived last Friday, when a number of scientists residing in the Genome Science Building...