Research Archive

Circulating Omega-6 and Omega-3 Polyunsaturated Fatty Acids in Painful Temporomandibular Disorder and Low Back Pain

This cross-sectional study examined relationships between PUFAs in circulating erythrocytes and 2 chronic idiopathic pain conditions: temporomandibular disorder (TMD) and low back pain in a community-based sample of 503 U.S. adults.

Surface-Initiated Passing-Through Polymerization on a Rubber Substrate: Supplying Monomer from Swollen Substrates

Here we use a combination of coarse-grained computer simulations and experimental techniques to demonstrate how this approach can be implemented, with swellable network-like substrates supplying monomers to the functionalized surface as they diffuse out of the swollen network.

SHAPE-enabled fragment-based ligand discovery for RNA

Here, we devise a technology that leverages fragment-based screening and SHAPE-MaP RNA structure probing to discover small-molecule fragments that bind an RNA structure of interest.

Uniquely Enabling Mechanism for Bis-oxazoline Copper(II)-Catalyzed Azidation of Pyranosides and Furanosides

This work reports a bis-oxazoline Cu2+ catalyst for the selective azidation of pyranosides and furanosides.

Photomediated RAFT step-growth polymerization with maleimide monomers

Photomediated RAFT step-growth polymerization was performed with and without the presence of a photocatalyst using a trithiocarbonate-based CTA and a maleimide monomer.

Development of Bioderived Alternatives to N95 Face Masks in a Remote Course-Based Undergraduate Research Experience

Here, through an at-home course-based undergraduate research experience (CURE), we demonstrate that alginate and soy-based materials are attractive alternatives for mask fabrication: stacking calcium ion-cross-linked alginate films with soy protein isolate sheets enables electrostatic and size-exclusion filtration.

Mechanisms of Foreign Body Response Mitigation by Nitric Oxide Release

In this study, we evaluated mediator, immune cell, and mRNA expression profiles in the local tissue microenvironment surrounding implanted sensors as a function of NO release, diabetes, and implantation duration.

Obesity reprograms the pulmonary polyunsaturated fatty acid-derived lipidome, transcriptome, and gene-oxylipin networks

Herein, we tested the hypothesis that obesity dysregulates pulmonary PUFA metabolism that is central to inflammation initiation and resolution.

Circulating polyunsaturated fatty acids, pressure pain thresholds, and nociplastic pain conditions

This study sought to determine whether free PUFAs found in red blood cells also play a role in nociceptive processing.

Chloride Oxidation by One- or Two-Photon Excitation of N-Phenylphenothiazine

Herein, two photocatalytic chloride oxidation pathways that involve either one- or consecutive two-photon excitation of N-phenylphenothiazine (PTH) are presented.

Carbazole-Based Hole Transport Polymer for Methylammonium-Free Tin–Lead Perovskite Solar Cells with Enhanced Efficiency and Stability

Herein, an easily synthesized polymer HTM poly[(phenyl)imino[9-(2-ethylhexyl)carbazole]-2,7-diyl] (CzAn) with a shallow highest occupied molecular orbital (HOMO) level of −4.95 eV is used in a p-i-n structure, methylammonium-free, Sn–Pb PSC to replace PEDOT:PSS.

Biosynthetic Origin of Formylaminooxyvinylglycine and Characterization of the Formyltransferase GvgI

We identify a formyltransferase gvgI that is required for the production of FVG and characterize the activity of this enzyme in vitro toward amino acids with a side chain amine.