Royce Murray Term Professor of ChemistryMurray Hall 2202G
Synthetic Organic Chemistry, Catalysis, Natural Product Synthesis
My research interests lie in the broadly defined fields of asymmetric catalysis and target-oriented synthesis. Concerning the area of asymmetric catalysis, my laboratory will focus primarily on the development of novel catalytic processes to access highly reactive intermediates under operationally mild conditions. Methods encompassing the general areas of electron transfer and atom abstraction are of particular interest. In the context of natural product synthesis, targets will be selected on the basis of their biological activity and structural complexity. Specifically, I am interested in complex molecules that inspire the development of new strategies and methods for their construction.
B.S., University of North Carolina at Charlotte, 2000; M.S., University of North Carolina at Charlotte, 2002; Ph.D., University of North Carolina at Chapel Hill, 2006; NIH Postdoctoral Fellow, Princeton University, 2007-2009; Eli Lilly New Faculty Award, 2009; Packard Fellowship in Science and Engineering, 2012; New Investigator Award in Organic Chemistry, sponsored by Boehringer Ingelheim, 2013; NSF CAREER Award, 2014-2019; Amgen Young Investigator Award, 2014
News & Publications
Here, we disclose a mild organophotoredox-catalyzed method for efficient cyanation of a broad spectrum of electron-rich arenes, including abundant and readily available veratroles and pyrogallol trimethyl ethers.
Herein, we communicate a strategy for the divergent functionalization of alkynes with photoexcited acridinium organic dyes, presumably via the formation of vinyl cation radicals as key intermediates.