Chemistry Innovation and Biological Discovery through Natural Product Total Synthesis
Mingji Dai
This talk will focus on our recent efforts in function and efficiency-driven total synthesis of medicinally important natural products. The target molecules include macrolides, alkaloids, and polycyclic diterpenoids. Novel and enabling synthetic strategies and methodologies toward these target molecules will be highlighted. Biological evaluation and target identification of the selected natural products and their analogs will be discussed as well. Overall, this talk will emphasize how we use natural product total synthesis to achieve chemistry innovation and biological discovery