Chemistry Course Descriptions – Advanced

CHEM 410. Instructional Methods in the Chemistry Classroom. 4 Credits.
Permission of the instructor. This course explores secondary school chemical education through current chemical education theory and classroom teaching. Students will develop a comprehensive approach to teaching chemistry content through student-centered activities.
Requisites: Prerequisites, CHEM 241, 251, 262, and 262L.
Gen Ed: EE-Field Work.
Grading Status: Letter Grade.


CHEM 420. Introduction to Polymer Chemistry. 3 Credits.
Chemical structure and nomenclature of macromolecules, synthesis of polymers, characteristic polymer properties.
Requisites: Prerequisite, CHEM 261 or 261H; pre- or corequisites, CHEM 262 or 262H, and 262L or 263L.
Grading Status: Letter Grade.
Same As: APPL 420.


CHEM 421. Synthesis of Polymers. 3 Credits.
Synthesis and reactions of polymers; various polymerization techniques.
Requisites: Prerequisites, CHEM 251 and 262 or 262H.
Grading Status: Letter Grade.
Same As: APPL 421.


CHEM 422. Physical Chemistry of Polymers. 3 Credits.
Polymerization and characterization of macromolecules in solution.
Requisites: Prerequisites, CHEM 420 and 481.
Grading Status: Letter Grade.
Same As: APPL 422.


CHEM 423. Intermediate Polymer Chemistry. 3 Credits.
Polymer dynamics, networks and gels.
Requisites: Prerequisite, CHEM 422.
Grading Status: Letter Grade.
Same As: APPL 423.


CHEM 425. Polymer Materials. 3 Credits.
Solid-state properties of polymers; polymer melts, glasses and crystals.
Requisites: Prerequisite, CHEM 421 or 422.
Grading Status: Letter Grade.


CHEM 430. Introduction to Biological Chemistry. 3 Credits.
The study of cellular processes including catalysts, metabolism, bioenergetics, and biochemical genetics. The structure and function of biological macromolecules involved in these processes is emphasized. Honors version available.
Requisites: Prerequisites, BIOL 101, and CHEM 262 or 262H.
Grading Status: Letter Grade.
Same As: BIOL 430.


CHEM 431. Macromolecular Structure and Metabolism. 3 Credits.
Structure of DNA and methods in biotechnology; DNA replication and repair; RNA structure, synthesis, localization and transcriptional reputation; protein structure/function, biosynthesis, modification, localization, and degradation.
Requisites: Prerequisites, BIOL 202 and CHEM 430.
Grading Status: Letter Grade.


CHEM 432. Metabolic Chemistry and Cellular Regulatory Networks. 3 Credits.
Biological membranes, membrane protein structure, transport phenomena; metabolic pathways, reaction themes, regulatory networks; metabolic transformations with carbohydrates, lipids, amino acids, and nucleotides; regulatory networks, signal transduction.
Requisites: Prerequisite, CHEM 430.
Grading Status: Letter Grade.


CHEM 433. Transport in Biological Systems. 1 Credit.
Permission of the instructor for undergraduates. Diffusion, sedimentation, electrophoresis, flow. Basic principles, theoretical methods, experimental techniques, role in biological function, current topics.
Requisites: Prerequisites, CHEM 430 and MATH 383.
Grading Status: Letter Grade.


CHEM 441. Intermediate Analytical Chemistry. 2 Credits.
Spectroscopy, electroanalytical chemistry, chromatography, thermal methods of analysis, signal processing.
Requisites: Prerequisites, CHEM 241, 241L, 262, and 480 or 481.
Grading Status: Letter Grade.


CHEM 441L. Intermediate Analytical Chemistry Laboratory. 2 Credits.
Experiments in spectroscopy, electroanalytical chemistry, chromatography, thermal methods of analysis, and signal processing. One four-hour laboratory a week and one one-hour lecture.
Requisites: Corequisite, CHEM 441.
Grading Status: Letter Grade.


CHEM 444. Separations. 3 Credits.
Theory and applications of equilibrium and nonequilibrium separation techniques. Extraction, countercurrent distribution, gas chromatography, column and plane chromatographic techniques, electrophoresis, ultra-centrifugation, and other separation methods.
Requisites: Prerequisites, CHEM 441 and CHEM 480 or 481.
Grading Status: Letter Grade.


CHEM 445. Electroanalytical Chemistry. 3 Credits.
Basic principles of electrochemical reactions, electroanalytical voltammetry as applied to analysis, the chemistry of heterogeneous electron transfers, and electrochemical instrumentation.
Requisites: Prerequisite, CHEM 480 or 481.
Grading Status: Letter Grade.


CHEM 446. Analytical Spectroscopy. 3 Credits.
Optical spectroscopic techniques for chemical analysis including conventional and laser-based methods. Absorption, fluorescence, scattering and nonlinear spectroscopies, instrumentation and signal processing.
Requisites: Prerequisites, CHEM 441 and 482.
Grading Status: Letter Grade.


CHEM 447. Bioanalytical Chemistry. 3 Credits.
Principles and applications of biospecific binding as a tool for performing selective chemical analysis.
Requisites: Prerequisite, CHEM 441.
Grading Status: Letter Grade.


CHEM 448. Mass Spectrometry. 3 Credits.
Fundamental theory of gaseous ion chemistry, instrumentation, combination with separation techniques, spectral interpretation for organic compounds, applications to biological and environmental chemistry.
Requisites: Prerequisite, CHEM 480 or 481.
Grading Status: Letter Grade.


CHEM 449. Microfabricated Chemical Measurement Systems. 3 Credits.
Introduction to micro and nanofabrication techniques, fluid and molecular transport at the micrometer to nanometer length scales, applications of microtechnology to chemical and biochemical measurements.
Requisites: Prerequisite, CHEM 441.
Grading Status: Letter Grade.


CHEM 450. Intermediate Inorganic Chemistry. 3 Credits.
Introduction to symmetry and group theory; bonding, electronic spectra, and reaction mechanisms of coordination complexes; organometallic complexes, reactions, and catalysis; bioinorganic chemistry.
Requisites: Prerequisite, CHEM 251.
Grading Status: Letter Grade.


CHEM 451. Theoretical Inorganic Chemistry. 3 Credits.
Chemical applications of symmetry and group theory, crystal field theory, molecular orbital theory. The first third of the course, corresponding to one credit hour, covers point symmetry, group theoretical foundations and character tables.
Requisites: Prerequisites, CHEM 262 or 262H and 450.
Grading Status: Letter Grade.


CHEM 452. Electronic Structure of Transition Metal Complexes. 3 Credits.
A detailed discussion of ligand field theory and the techniques that rely on the theoretical development of ligand field theory, including electronic spectroscopy, electron paramagnetic resonance spectroscopy, and magnetism.
Requisites: Prerequisite, CHEM 451.
Grading Status: Letter Grade.


CHEM 453. Physical Methods in Inorganic Chemistry. 3 Credits.
Introduction to the physical techniques used for the characterization and study of inorganic compounds. Topics typically include nuclear magnetic resonance spectroscopy, vibrational spectroscopy, diffraction, Mossbauer spectroscopy, X-ray photoelectron spectroscopy, and inorganic electrochemistry.
Requisites: Prerequisite, CHEM 451.
Grading Status: Letter Grade.


CHEM 460. Intermediate Organic Chemistry. 3 Credits.
Modern topics in organic chemistry. Honors version available.
Requisites: Prerequisite, CHEM 262 or 262H.
Grading Status: Letter Grade.


CHEM 465. Mechanisms of Organic and Inorganic Reactions. 4 Credits.
Kinetics and thermodynamics, free energy relationships, isotope effects, acidity and basicity, kinetics and mechanisms of substitution reactions, one- and two-electron transfer processes, principles and applications of photochemistry, organometallic reaction mechanisms.
Requisites: Prerequisite, CHEM 450.

Grading Status: Letter Grade.


CHEM 466. Advanced Organic Chemistry I. 3 Credits.
A survey of fundamental organic reactions including substitutions, additions, elimination, and rearrangements; static and dynamic stereochemistry; conformational analysis; molecular orbital concepts and orbital symmetry.
Requisites: Prerequisite, CHEM 460.
Grading Status: Letter Grade.


CHEM 467. Advanced Organic Chemistry II. 2 Credits.
Spectroscopic methods of analysis with emphasis on elucidation of the structure of organic molecules: 1H and 13C NMR, infrared, ultraviolet, ORD-CD, mass, and photoelectron spectroscopy.
Requisites: Prerequisite, CHEM 466.
Grading Status: Letter Grade.


CHEM 468. Synthetic Aspects of Organic Chemistry. 3 Credits.
Modern synthetic methods and their application to the synthesis of complicated molecules.
Requisites: Prerequisite, CHEM 466.
Grading Status: Letter Grade.


CHEM 469. Organometallics and Catalysis. 3 Credits.
Structure and reactivity of organometallic complexes and their role in modern catalytic reactions.
Requisites: Prerequisites, CHEM 450 and 466.
Grading Status: Letter Grade.


CHEM 470. Fundamentals of Materials Science. 3 Credits.
Prerequisite, CHEM 482; or Crystal geometry, diffusion in solids, mechanical properties of solids, electrical conduction in solids, thermal properties of materials, phase equilibria.
Requisites: prerequisite, PHYS 128 and pre- or corequisite, PHYS 441.
Grading Status: Letter Grade.
Same As: APPL 470.


CHEM 471. Mathematical Techniques for Chemists. 3 Credits.
Knowledge of differential and integral calculus. Chemical applications of higher mathematics.
Requisites: Prerequisite, MATH 383; permission of the instructor for students lacking the prerequisite.
Grading Status: Letter Grade.


CHEM 472. Chemistry and Physics of Electronic Materials Processing. 3 Credits.
Permission of the instructor. A survey of materials processing and characterization used in fabricating microelectronic devices. Crystal growth, thin film deposition and etching, and microlithography.
Requisites: Prerequisite, CHEM 482 or PHYS 117 or 119.
Grading Status: Letter Grade.
Same As: PHYS 472, APPL 472.


CHEM 473. Chemistry and Physics of Surfaces. 3 Credits.
The structural and energetic nature of surface states and sites, experimental surface measurements, reactions on surfaces including bonding to surfaces and adsorption, interfaces.
Requisites: Prerequisite, CHEM 470.
Grading Status: Letter Grade.
Same As: APPL 473.


CHEM 480. Introduction to Biophysical Chemistry. 3 Credits.
Does not carry credit toward graduate work in chemistry or credit toward any track of the B.S. degree with a major in chemistry. Application of thermodynamics to biochemical processes, enzyme kinetics, properties of biopolymers in solution.
Requisites: Prerequisites, CHEM 261 or 261H, MATH 232, and PHYS 105.
Grading Status: Letter Grade.


CHEM 481. Physical Chemistry I. 3 Credits.
Thermodynamics, kinetic theory, chemical kinetics.
Requisites: Prerequisites, CHEM 102 or 102H, PHYS 116; pre- or corequisites, MATH 383 and PHYS 117; C- or better required in chemistry course prerequisites.
Grading Status: Letter Grade.


CHEM 481L. Physical Chemistry Laboratory I. 2 Credits.
Experiments in physical chemistry. Solving thermodynamic and quantum mechanical problems using computer simulations. One three-hour laboratory and a single one-hour lecture each week.
Requisites: Prerequisite, CHEM 482.
Grading Status: Letter Grade.


CHEM 482. Physical Chemistry II. 3 Credits.
Introduction to quantum mechanics, atomic and molecular structure, spectroscopy, statistical mechanics.

Requisites: Prerequisite, CHEM 481.
Grading Status: Letter Grade.


CHEM 482L. Physical Chemistry Laboratory II. 2 Credits.
Experiments in physical chemistry. One four-hour laboratory each week.
Requisites: Prerequisite, CHEM 482; pre- or corequisite, CHEM 481L.
Grading Status: Letter Grade.


CHEM 484. Thermodynamics and Introduction to Statistical Thermodynamics. 1-21 Credits.
Thermodynamics, followed by an introduction to the classical and quantum statistical mechanics and their application to simple systems. The section on thermodynamics can be taken separately for one hour Credit.
Requisites: Prerequisite, CHEM 482.
Grading Status: Letter Grade.


CHEM 485. Chemical Dynamics. 3 Credits.
Experimental and theoretical aspects of atomic and molecular reaction dynamics.
Requisites: Prerequisites, CHEM 481 and 482.
Grading Status: Letter Grade.


CHEM 486. Introduction to Quantum Chemistry. 3 Credits.
Introduction to the principles of quantum mechanics. Approximation methods, angular momentum, simple atoms and molecules.
Requisites: Prerequisites, CHEM 481 and 482.
Grading Status: Letter Grade.


CHEM 487. Introduction to Molecular Spectroscopy. 3 Credits.
Interaction of radiation with matter; selection rules; rotational, vibrational, and electronic spectra of molecules; laser based spectroscopy and nonlinear optical effects.
Requisites: Prerequisite, CHEM 486.
Grading Status: Letter Grade.


CHEM 488. Quantum Chemistry. 3 Credits.
Applications of quantum mechanics to chemistry. Molecular structure, time-dependent perturbation theory, interaction of radiation with matter.
Requisites: Prerequisite, CHEM 486.
Grading Status: Letter Grade.


CHEM 489. Statistical Mechanics. 3 Credits.
Applications of statistical mechanics to chemistry. Ensemble formalism, condensed phases, nonequilibrium processes.
Requisites: Prerequisite, CHEM 484.
Grading Status: Letter Grade.


CHEM 520L. Polymer Chemistry Laboratory. 2 Credits.
Various polymerization techniques and characterization methods. One four-hour laboratory each week.
Requisites: Pre- or corequisite, CHEM 420 or 421 or 425.
Grading Status: Letter Grade.
Same As: APPL 520L.


CHEM 530L. Laboratory Techniques for Biochemistry. 3 Credits.
An introduction to chemical techniques and research procedures of use in the fields of protein and nucleic acid chemistry. Two four-hour laboratories and one one-hour lecture a week.
Requisites: Pre- or corequisite, CHEM 430.
Grading Status: Letter Grade.


CHEM 541. Analytical Microscopy. 3 Credits.
Introduction to microscopy techniques utilized in the analysis of chemical and biological samples with a focus on light, electron, and atomic force microscopy. Permission of instructor required for those missing prerequisites.
Grading Status: Letter Grade.


CHEM 550L. Synthetic Chemistry Laboratory I. 2 Credits.
A laboratory devoted to synthesis and characterization of inorganic complexes and materials. A four-hour synthesis laboratory, a characterization laboratory outside of the regular laboratory period, and a one-hour recitation each week.
Requisites: Prerequisites, CHEM 241L or 245L, 251, and 262L or 263L.
Gen Ed: CI.
Grading Status: Letter Grade.


CHEM 560L. Synthetic Organic Laboratory. 2 Credits.
An advanced synthesis laboratory focused on topics in organic chemistry. A four-hour synthesis laboratory, a characterization laboratory outside of the regular laboratory period, and a one-hour recitation each week.
Requisites: Prerequisites, CHEM 241L, 245L, 262L, 263L.
Grading Status: Letter Grade.


CHEM 692H. Senior Honors Thesis. 3 Credits.
CHEM 395 must have been in the same laboratory as 692H. Senior majors only. Required of all candidates for honors or highest honors.
Requisites: Prerequisite, six credit hours of CHEM 395.
Grading Status: Letter Grade.