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The Redinbo Group

The Redinbo Laboratory uses the tools of structural, molecular and chemical biology to examine a range of dynamic cellular processes central to human health. Current projects include the discovery of new antimicrobials targeted to drug-resistant bacteria, the design of novel proteins engineered to detect and eliminate toxic chemicals, and the development of small-molecule to cell-based methods to improve anticancer chemotherapeutics. In addition, we continue to focus on determining the crystal structures of macromolecular complexes, including those involving human nuclear receptors central to transcriptional regulation, bacterial proteins involved in DNA manipulation and human cell contact, and enzymes central to key cellular processes.

The Lawrence Group

The Lawrence Group works at the interface between organic synthesis and cell biology. In fact, half the group resides in Chemistry's Kenan Labs and the other half can be found in the newly opened multidisciplinary Genetic Medicine Building in the medical school complex. The lab focuses on the design, synthesis, characterization, and application of probes of intracellular chemistry. Research interests include new diagnostic strategies for cancer, sensors of signaling pathways, mitochondrial proteomics, the molecular basis of memory and learning, and the control of gene expression in living animals.