The Gagné Lab is interested in the development of new synthetic methods for complex bond constructions. To mimic sterol biosynthesis, we have developed several "carbophilic" late metal catalysts (Pd, Pt, and Au) for alkene and allene activation, while in other projects we seek new catalysts for glycosidic C-O bond activation. The goal in this latter project is to use polysaccharides as renewable feedstocks for complex molecule synthesis. A third major thrust is in dynamic combinatorial chemistry (DCC), a dynamic templating strategy that selects for new receptors under competitive binding conditions. This strategy is additionally being used for new catalyst discovery.
Associate professor Mark Schoenfisch in the analytical division, along with two of his senior graduate students, Susan Deupree and Evan Hetrick, recently returned from the Eighth World Biomaterials Congress, held this year in Amsterdam. The Congress featured posters and presentations from over 2800 papers, including three from the Schoenfisch group. Research presented by our lab showcased the efficacy of novel nitric oxide-releasing nanoparticles as anti-biofilm agents, the ability of these materials to aid in mediating the biocompatibility of implantable sensors, as well as an atomic force microscopy study of the mechanism of nitric oxide’s antimicrobial action.
Apart from all the work happening inside the structure, such as with ductwork, electrical, stairs, air handling equipment, and the million valves and pipes that fill the space above the future ceilings, the brickworkers on the outside of the building are quickly climbing up the facade, one row of bricks at a time. The masonry work on both East and West walls are now virtually complete.
These images were taken on August 19th. Roof covering is laid down, and windows are being put in. The connection between Caudill Labs and the new building is now covered and glassed. Next, openings will be made in the walls on the Caudill side to truly connect the new building as shown below. Both external and internal work plans are progressing on schedule.
Connecting walkway from "New Venable" to Caudill Labs
The Science Complex Courtyard with Kenan Labs in the background
External view of the connecting walkway from "New Venable" to Caudill Labs
Miles and miles of wires and pipes...
Future classrooms are beginning to take shape.
The above images chronologically depict the demolition of Venable Hall, followed by the site-preparation for and the construction of the Physical Sciences Building.
Follow the progress at the new Venable Hall construction site with our live webcam. The camera is located on the observation deck on top of Chapman Hall.
Although Old Venable Hall has been reduced to rubble, you still have an opportunity to retain a piece of the past, touch your memories and support Carolina Chemistry and the construction of New Venable Hall. We rescued a limited number of bricks from the east facade of Old Venable hall. Scrubbed meticulously clean and prepared to exacting standards by Alpha Chi Sigma volunteers, these rare artifacts are being offered to Venable alumni either as Chancellor's Edition Bricks, only 25 to be offered, Limited Edition Brick, only 250 to be offered, or as the Venable Brick Slice paper weight. Thank you for your continued support of UNC Chemistry.
To Donate to Chemistry and receive your Venable Hall memorabilia:
For additional information, please call 919-962-6193